Description

A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G).

Chemical properties

Chemical formula Net charge Average mass
C11H15N5O5 0 297.26730
nelarabine

Nomenclature

IUPAC SMILES InChI InChIKey Synonyms
9-(beta-D-arabinofuranosyl)-6-methoxy-9H-purin-2-amine COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/m1/s1 IXOXBSCIXZEQEQ-UHTZMRCNSA-N
  • 2-amino-9-beta-d-arabinofuranosyl-6-methoxy-9h-purine
  • arranon
  • nelzarabine